PUS1 antibody (C-Term)

Catalog No. ABIN183468

Product Details anti-PUS1 Antibody

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PUS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PTIVSTERDE RSMAQWLNTL PIHNFSGTAL GAADTGAKVP SSLEGSEGDG

Predicted Reactivity: Human: 92%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PUS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 393 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PUS1

Target: PUS1 (Pseudouridylate Synthase 1 (PUS1))

Alternative Name: PUS1 (PUS1 Products)

Synonyms: PUS1 antibody, A730013B20Rik antibody, MPUS1 antibody, mPus1p antibody, MLASA1 antibody, pseudouridylate synthase 1 antibody, pseudouridylate synthase 1, putative antibody, pseudouridine synthase 1 antibody, PUS1 antibody, PVX_093530 antibody, PKH_011400 antibody, Pus1 antibody

Background: Pus1 converts specific uridines to PSI in a number of tRNA substrates. Pus1 acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Pus1 is involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA.
Alias Symbols: MPUS1, mPus1p, A730013B20Rik
Protein Interaction Partner: Rarg, Sra1, Rarb,
Protein Size: 423

Molecular Weight: 48 kDa

Gene ID: 56361

NCBI Accession: NM_001025562, NP_001020733

UniProt: Q791J1