EOMES antibody (C-Term)

Catalog No. ABIN2779928

Product Details anti-EOMES Antibody

Target: EOMES (Eomesodermin (EOMES))

Binding Specificity: C-Term

Reactivity: Mouse, Rat, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EOMES antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SSDSGVYNSA CKRKRLSPST PSNGNSPPIK CEDINTEEYS KDTSKGMGAY

Predicted Reactivity: Cow: 80%, Dog: 80%, Guinea Pig: 80%, Mouse: 100%, Rat: 87%

Characteristics: This is a rabbit polyclonal antibody against Eomes. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human Eomes

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 707 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EOMES

Target: EOMES (Eomesodermin (EOMES))

Alternative Name: Eomes (EOMES Products)

Synonyms: TBR2 antibody, eom antibody, eomes antibody, EOMES antibody, xeomes antibody, tbr2 antibody, C77258 antibody, TBR-2 antibody, Tbr2 antibody, eomesodermin antibody, eomesodermin homolog a antibody, eomesodermin L homeolog antibody, EOMES antibody, eomesa antibody, Eomes antibody, eomes.L antibody, eomes antibody

Background: Eomes functions as a transcriptional activator playing a crucial role during development. Eomes functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification.Eomes plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Eomes also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes.
Alias Symbols: C77258, Tbr2, TBR-2
Protein Size: 707

Molecular Weight: 75 kDa

Gene ID: 13813

NCBI Accession: NM_010136, NP_034266

UniProt: O54839

Pathways: Stem Cell Maintenance