TFAM antibody (C-Term)
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- Target See all TFAM Antibodies
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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Binding Specificity
- C-Term
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Reactivity
- Mouse, Rat, Rabbit, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TFAM antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- FQEAKDDSAQ GKLKLVNEAW KNLSPEEKQA YIQLAKDDRI RYDNEMKSWE
- Predicted Reactivity
- Cow: 79%, Mouse: 100%, Rabbit: 79%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against Tfam. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of mouse Tfam
- Top Product
- Discover our top product TFAM Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 243 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- Alternative Name
- Tfam (TFAM Products)
- Background
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TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
Alias Symbols: AI661103, Hmgts, mtTFA, tsHMG
Protein Interaction Partner: C1QBP, SNCA,
Protein Size: 243 - Molecular Weight
- 27 kDa
- Gene ID
- 21780
- NCBI Accession
- NM_009360, NP_033386
- UniProt
- P40630
- Pathways
- Chromatin Binding
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