PTRF antibody (Middle Region)

Catalog No. ABIN2779886

Product Details anti-PTRF Antibody

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTRF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SEALPEKEGD ELGEGERPED DTAAIELSSD EAVEVEEVIE ESRAERIKRS

Predicted Reactivity: Cow: 85%, Dog: 92%, Horse: 92%, Human: 90%, Mouse: 100%, Rabbit: 85%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against PTRF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse PTRF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 392 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTRF

Target: PTRF (Polymerase I and Transcript Release Factor (PTRF))

Alternative Name: PTRF (PTRF Products)

Synonyms: MGC53017 antibody, MGC89141 antibody, PTRF antibody, fd20g07 antibody, ptrf antibody, wu:fd20g07 antibody, zgc:162917 antibody, CAVIN antibody, CAVIN1 antibody, CGL4 antibody, cavin-1 antibody, 2310075E07Rik antibody, AW546441 antibody, Cav-p60 antibody, Cavin antibody, caveolae associated protein 1 L homeolog antibody, polymerase I and transcript release factor antibody, caveolae associated protein 1 antibody, caveolae associated protein 1b antibody, caveolae associated 1 antibody, cavin1.L antibody, PTRF antibody, cavin1 antibody, CAVIN1 antibody, cavin1b antibody, Cavin1 antibody

Background: In mouse, pausing of elongation complexes is mediated by the transcription termination factor TTF-I bound to the 'Sal box' terminator downstream of the rDNA transcription unit. PTRF is a Pol I and transcript release factor for dissociation of paused ternary complexes.
Alias Symbols: Cavin, Cav-p60, AW546441, 2310075E07Rik
Protein Interaction Partner: Fbxo32, Dmd, Htt,
Protein Size: 392

Molecular Weight: 43 kDa

Gene ID: 19285

NCBI Accession: NM_008986, NP_033012

UniProt: O54724