IRF1 antibody (Middle Region)
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- Target See all IRF1 Antibodies
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Sheep, Horse, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IRF1 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DIIPDSTTDL YNLQVSPMPS TSEAATDEDE EGKIAEDLMK LFEQSEWQPT
- Predicted Reactivity
- Cow: 85%, Dog: 83%, Guinea Pig: 92%, Horse: 83%, Human: 83%, Mouse: 100%, Rabbit: 85%, Rat: 92%, Sheep: 85%, Yeast: 83%
- Characteristics
- This is a rabbit polyclonal antibody against Irf1. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide corresponding to a region of Mouse
- Top Product
- Discover our top product IRF1 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 329 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IRF1 (Interferon Regulatory Factor 1 (IRF1))
- Alternative Name
- Irf1 (IRF1 Products)
- Synonyms
- irf1 antibody, zgc:136945 antibody, IRF1 antibody, irf11 antibody, zgc:103566 antibody, IRF-1 antibody, MAR antibody, AU020929 antibody, Irf-1 antibody, interferon regulatory factor 1 antibody, interferon regulatory factor 1a antibody, interferon regulatory factor 1b antibody, IRF1 antibody, irf1a antibody, irf1b antibody, Irf1 antibody
- Background
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Irf1 specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes.Irf1 acts as a tumor suppressor.
Alias Symbols: AU020929, Irf-1
Protein Interaction Partner: Ubc, Sumo1, Ube2i, Pias3, Tbk1, Polr2a,
Protein Size: 329 - Molecular Weight
- 37 kDa
- Gene ID
- 16362
- NCBI Accession
- NM_008390, NP_032416
- UniProt
- P15314
- Pathways
- Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy
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