HSF4 antibody (Middle Region)

Catalog No. ABIN2779779

Product Details anti-HSF4 Antibody

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Binding Specificity: Middle Region

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSF4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VTLRQSHGQQ HRVIGKLIQC LFGPLQAGPS NAGGKRKLSL MLDEGSSCPT

Predicted Reactivity: Human: 100%, Rabbit: 92%

Characteristics: This is a rabbit polyclonal antibody against HSF4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HSF4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 463 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HSF4 antibody (ABIN2779779)

Lazrek, Goffard, Schanen, Karquel, Bocket, Lion, Devaux, Hedouin, Gosset, Hober: "Detection of hepatitis C virus antibodies and RNA among medicolegal autopsy cases in Northern France." in: Diagnostic microbiology and infectious disease, Vol. 55, Issue 1, pp. 55-8, (2006) (PubMed).

Target Details for HSF4

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Alternative Name: HSF4 (HSF4 Products)

Synonyms: CTM antibody, CTRCT5 antibody, HSF 4 antibody, HSTF 4 antibody, HSTF4 antibody, ldis1 antibody, mHSF4 antibody, zgc:113344 antibody, heat shock transcription factor 4 antibody, HSF4 antibody, Hsf4 antibody, hsf4 antibody

Background: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.
Alias Symbols: CTM
Protein Interaction Partner: SESTD1, MYO15A, TIMM13, SUGT1, RABEP1, TARBP1, HSF2, HSF1, FKBP5, DUSP26, MAPK1, SUMO1, ZBED8, NUDT21, CDK2AP2, BCL6, SMARCA4, SLC27A5, HSF4, MAPK3, MAPK8, MAPK14,
Protein Size: 463

Molecular Weight: 50 kDa

Gene ID: 3299

NCBI Accession: NM_001538, NP_001529

Pathways: MAPK Signaling