HOXD12 antibody (N-Term)

Catalog No. ABIN2779774

Product Details anti-HOXD12 Antibody

Target: HOXD12 (Homeobox D12 (HOXD12))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Horse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXD12 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MCERSLYRAG YVGSLLNLQS PDSFYFSNLR PNGGQLAALP PISYPRGALP

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HOXD12. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXD12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 279 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HOXD12 antibody (ABIN2779774)

Illig, Fritsch, Schwarzer: "Spatio-temporal expression of HOX genes in human hindgut development." in: Developmental dynamics : an official publication of the American Association of Anatomists, Vol. 242, Issue 1, pp. 53-66, (2012) (PubMed).

Target Details for HOXD12

Target: HOXD12 (Homeobox D12 (HOXD12))

Alternative Name: HOXD12 (HOXD12 Products)

Synonyms: HOX4H antibody, Hox-4.7 antibody, Hox-5.6 antibody, HOXD12 antibody, HOX-D12 antibody, hoxd-12 antibody, hoxd12 antibody, HoxD12a antibody, homeobox D12 antibody, homeo box D12 antibody, homeobox D12a antibody, HOXD12 antibody, Hoxd12 antibody, hoxd12a antibody, hoxd12 antibody

Background: HOXD12 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.
Alias Symbols: HOX4H
Protein Interaction Partner: TRAF1, CREBBP, MAFF, MAFG, MEIS1, MAFB, MAFK, MAF,
Protein Size: 279

Molecular Weight: 30 kDa

Gene ID: 3238

NCBI Accession: NM_021193, NP_067016

UniProt: P35452