HDAC2 antibody (C-Term)
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- Target See all HDAC2 Antibodies
- HDAC2 (Histone Deacetylase 2 (HDAC2))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Horse, Dog, Pig, Saccharomyces cerevisiae
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HDAC2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- EEFSDSEDEG EGGRRNVADH KKGAKKARIE EDKKETEDKK TDVKEEDKSK
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%
- Characteristics
- This is a rabbit polyclonal antibody against HDAC2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human HDAC2
- Top Product
- Discover our top product HDAC2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 488 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HDAC2 (Histone Deacetylase 2 (HDAC2))
- Alternative Name
- HDAC2 (HDAC2 Products)
- Synonyms
- HD2 antibody, RPD3 antibody, YAF1 antibody, D10Wsu179e antibody, Yy1bp antibody, mRPD3 antibody, HISTONE DEACETYLASE antibody, T1N24.9 antibody, T1N24_9 antibody, histone deacetylase 2 antibody, histone deacetylase 2 antibody, histone deacetylase 2 S homeolog antibody, HDAC2 antibody, Hdac2 antibody, hdac2.S antibody, HDA2 antibody
- Background
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Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
Alias Symbols: HD2, RPD3, YAF1
Protein Interaction Partner: BRCA1, SUMO1, UBC, SMAD7, SMAD2, MXD1, NCOR2, SUMO2, SFPQ, KDM5A, HDAC1, DDB1, CUL4B, CHFR, KDM1A, KDM5B, NFE2L2, PRDM6, DNMT3B, DNMT1, NACC2, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, PRDM1, EED, RNF2, SP1, CHD4, CHD3, ACTL6A, C16orf87, HMG20A, HMG20B, C
Protein Size: 488 - Molecular Weight
- 55 kDa
- Gene ID
- 3066
- NCBI Accession
- NM_001527, NP_001518
- UniProt
- Q92769
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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