HINFP antibody (Middle Region)

Catalog No. ABIN2779711

Product Details anti-HINFP Antibody

Target: HINFP (Histone H4 Transcription Factor (HINFP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HINFP antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FKDRSKLREH LRSHTQEKVV ACPTCGGMFA NNTKFLDHIR RQTSLDQQHF

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against MIZF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MIZF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 517 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HINFP

Target: HINFP (Histone H4 Transcription Factor (HINFP))

Alternative Name: MIZF (HINFP Products)

Synonyms: HiNF-P antibody, MIZF antibody, ZNF743 antibody, mizf antibody, wu:fi67c06 antibody, zgc:66200 antibody, AA589481 antibody, Mizf antibody, RGD1311492 antibody, histone H4 transcription factor antibody, histone H4 transcription factor S homeolog antibody, HINFP antibody, hinfp antibody, hinfp.S antibody, Hinfp antibody

Background: MIZF interacts with methyl-CpG-binding protein-2 (MBD2, MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.MIZF interacts with methyl-CpG-binding protein-2 (MBD2, MIM 603547), a component of the MeCP1 histone deacetylase (HDAC) complex, and plays a role in DNA methylation and transcription repression.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-62 BF726036.1 1-62 63-1549 BC017234.2 47-1533 1550-2058 AK056362.1 1518-2026 2059-2202 BC001073.2 2085-2228
Alias Symbols: DKFZP434F162, HiNF-P, ZNF743, MIZF
Protein Interaction Partner: POM121C, CDYL2, RBM17, RPUSD4, THAP7, RBM26, MIF4GD, NPDC1, TRIM44, ELP4, NIPBL, SRRM2, PRRC2C, MORF4L1, ZNHIT1, MDC1, EFTUD2, TTF2, U2AF1, TLE3, TRA2B, MKI67, JUND, GSPT1, ATN1, SREBF2, NPAT, MBD2, TRAF2, HDAC1, DHX9,
Protein Size: 517

Molecular Weight: 60 kDa

Gene ID: 25988

NCBI Accession: NM_198971, NP_945322

UniProt: Q9BQA5

Pathways: Chromatin Binding