FOSB antibody (C-Term)

Catalog No. ABIN2779692

Product Details anti-FOSB Antibody

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOSB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DLPGSAPAKE DGFSWLLPPP PPPPLPFQTS QDAPPNLTAS LFTHSEVQVL

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 92%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against FOSB. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOSB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 338 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FOSB

Target: FOSB (FBJ Murine Osteosarcoma Viral Oncogene Homolog B (FOSB))

Alternative Name: FOSB (FOSB Products)

Synonyms: FOSB antibody, zgc:92354 antibody, AP-1 antibody, G0S3 antibody, GOS3 antibody, GOSB antibody, fra-2 antibody, FBJ murine osteosarcoma viral oncogene homolog B antibody, FosB proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene B antibody, FOSB antibody, fosb antibody, Fosb antibody

Background: The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. They are leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
Alias Symbols: AP-1, G0S3, GOS3, GOSB
Protein Interaction Partner: BAG3, SRA1, EP300, CREBBP, JUND, JUNB,
Protein Size: 338

Molecular Weight: 36 kDa

Gene ID: 2354

NCBI Accession: NM_006732, NP_006723

UniProt: P53539