GRIP1 antibody (N-Term)

Catalog No. ABIN2779681

Product Details anti-GRIP1 Antibody

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Rabbit, Dog, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MIAVSFKCRC QILRRLTKDE SPYTKSASQT KPPDGALAVR RQSIPEEFKG

Predicted Reactivity: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GRIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GRIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1061 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GRIP1 antibody (ABIN2779681)

Sugatani, Nishitani, Yamakawa, Yoshinari, Sueyoshi, Negishi, Miwa: "Transcriptional regulation of human UGT1A1 gene expression: activated glucocorticoid receptor enhances constitutive androstane receptor/pregnane X receptor-mediated UDP-glucuronosyltransferase 1A1 regulation with glucocorticoid receptor-interacting protei" in: Molecular pharmacology, Vol. 67, Issue 3, pp. 845-55, (2005) (PubMed).

Target Details for GRIP1

Target: GRIP1 (Glutamate Receptor Interacting Protein 1 (GRIP1))

Alternative Name: GRIP1 (GRIP1 Products)

Background: GRIP1 is a steroid receptor coactivator family (SRC) member. SRC proteins comprise a well-characterized family of nuclear receptor (NR) coactivators that increase transcriptional activation by NRs via covalent modification of chromatin proteins and recruitment of other coactivators.
Protein Interaction Partner: GPR37, LATS2, YWHAB, PRKD2, GRIA2, RXRB, UBE2I, LRRFIP1, CTNNB1, NCOA6, CREBBP, PRMT1, EFNA5, CARM1, VDR, RXRA, PPARG, ESR1, THRA, HIST1H3A, EP300, GRIP1, EHMT2, UBC, SMAD3, HDAC1, NR3C1, PICK1, IRF3, CSPG4, EFNB2, FLII, AR, EFNB1, GRIPAP1, NUMBL, GRM3, G
Protein Size: 1061

Molecular Weight: 117 kDa

Gene ID: 23426

NCBI Accession: XM_290559, XP_290559

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway