SIN3A antibody (N-Term)

Catalog No. ABIN2779673

Product Details anti-SIN3A Antibody

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIN3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KRRLDDQESP VYAAQQRRIP GSTEAFPHQH RVLAPAPPVY EAVSETMQSA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SIN3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SIN3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1273 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SIN3A

Target: SIN3A (SIN3 homolog A, transcription regulator (SIN3A))

Alternative Name: SIN3A (SIN3A Products)

Background: SIN3A is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZP434K2235, FLJ90319, KIAA0700
Protein Interaction Partner: CHFR, HDAC1, DDB1, CUL4B, HIF1A, UBC, ZBTB16, NEDD8, SUMO1, EED, SHFM1, MAD1L1, STAT3, TAL1, HDAC2, BHLHE40, ESR1, SAP30L, BRMS1, SAP30, RBBP4, KLF11, EPAS1, SNCA, S100A10, NOTCH2, THADA, SEPT11, TTLL12, AHCYL1, PDLIM5, SEC22B, SLC9A3R2, SF1, TP53, TOM1L2
Protein Size: 1273

Molecular Weight: 145 kDa

Gene ID: 25942

NCBI Accession: NM_015477, NP_056292

UniProt: Q96ST3

Pathways: Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha