CBX5 antibody (Middle Region)

Catalog No. ABIN2779672

Product Details anti-CBX5 Antibody

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KYKKMKEGEN NKPREKSESN KRKSNFSNSA DDIKSKKKRE QSNDIARGFE

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against CBX5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBX5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 191 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5 (CBX5 Products)

Synonyms: HP1 antibody, HP1A antibody, id:ibd2026 antibody, wu:fc63e02 antibody, wu:fe47g12 antibody, wu:fi03h05 antibody, zgc:158601 antibody, CBX5 antibody, cbx5 antibody, MGC64354 antibody, 2610029O15Rik antibody, C75991 antibody, Hp1a antibody, Hp1alpha antibody, chromobox 5 antibody, chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody, chromobox 5 S homeolog antibody, CBX5 antibody, cbx5 antibody, Cbx5 antibody, cbx5.S antibody

Background: CBX5 is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing.
Alias Symbols: HP1, HP1A
Protein Interaction Partner: SUV39H1, SP100, SUV39H2, WHSC1L1, VPS28, GOLGA8EP, SENP7, TRIM28, HIST3H3, RARA, UBC, ZBTB16, MDM2, XRN1, SRPK2, SRPK1, PRR14, EHMT2, MCC, TCEB1, TRIM39, BGLAP, BCL7A, ACTL6A, MIS12, ZNF747, ZNF649, WIZ, ZNF462, ZNF302, LRIF1, CDCA8, ZNF280D, AHDC1, NARF,
Protein Size: 191

Molecular Weight: 22 kDa

Gene ID: 23468

NCBI Accession: NM_012117, NP_036249

UniProt: P45973