SUV39H1 antibody (N-Term)

Catalog No. ABIN2779665

Product Details anti-SUV39H1 Antibody

Target: SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUV39H1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RHLDPSLANY LVQKAKQRRA LRRWEQELNA KRSHLGRITV ENEVDLDGPP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SUV39H1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SUV39H1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SUV39H1

Target: SUV39H1 (Suppressor of Variegation 3-9 Homolog 1 (Drosophila) (SUV39H1))

Alternative Name: SUV39H1 (SUV39H1 Products)

Synonyms: H3-K9-HMTase 1 antibody, KMT1A antibody, MG44 antibody, SUV39H antibody, AI852103 antibody, AL022883 antibody, DXHXS7466e antibody, mIS6 antibody, RGD1565028 antibody, kmt1a antibody, suv39h antibody, fe02c04 antibody, suv39h1 antibody, wu:fe02c04 antibody, zgc:101027 antibody, fe47h06 antibody, wu:fb18a10 antibody, wu:fe47h06 antibody, zgc:136593 antibody, suppressor of variegation 3-9 homolog 1 antibody, suppressor of variegation 3-9 homolog 1 (Drosophila) antibody, suppressor of variegation 3-9 homolog 1 L homeolog antibody, suppressor of variegation 3-9 homolog 1a antibody, suppressor of variegation 3-9 homolog 1b antibody, SUV39H1 antibody, Suv39h1 antibody, suv39h1.L antibody, suv39h1a antibody, suv39h1b antibody

Background: SUV39H1, a human homolog of the Drosophila position effect variegation modifier Su(var)3-9 and of the S. pombe silencing factor clr4, encodes a heterochromatic protein that transiently accumulates at centromeric positions during mitosis. This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KMT1A, MG44, SUV39H
Protein Interaction Partner: LZTS2, CEP70, HOOK2, CBX5, KRTAP10-7, HIST2H3A, CDCA4, KLHDC4, GTPBP2, ZNF581, ZCCHC17, CRBN, ING4, DCAF8, KLF15, KLHL20, PHF19, IL16, IGFBP4, ID2, ID1, HOXC4, HOXA1, FYN, FUS, EZH2, CLK3, ATP6V1B1, ATF3, GTF2H2C_2, H3F3C, LHX8, STX19, C17orf82, ZNF829, C
Protein Size: 412

Molecular Weight: 48 kDa

Gene ID: 6839

NCBI Accession: NM_003173, NP_003164

UniProt: O43463