SIRT7 antibody (C-Term)
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- Target See all SIRT7 Antibodies
- SIRT7 (Sirtuin 7 (SIRT7))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Dog, Cow, Horse, Pig, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIRT7 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- DVMRLLMAEL GLEIPAYSRW QDPIFSLATP LRAGEEGSHS RKSLCRSREE
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SIRT7. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7
- Top Product
- Discover our top product SIRT7 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 400 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SIRT7 (Sirtuin 7 (SIRT7))
- Alternative Name
- SIRT7 (SIRT7 Products)
- Synonyms
- SIRT7 antibody, LOC796135 antibody, SIR2L7 antibody, sirtuin 7 antibody, phosphate cytidylyltransferase 2, ethanolamine antibody, SIRT7 antibody, sirt7 antibody, PCYT2 antibody, Sirt7 antibody
- Background
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SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.
Alias Symbols: SIR2L7
Protein Interaction Partner: DDB1, VPRBP, APP, NOL6, YTHDC2, DDX31, RBM15, ANAPC1, NSD1, NOC3L, UBE2O, RBM25, CCAR2, CHD8, BEND3, PHRF1, DHX37, NUFIP2, CGN, XPO5, LRRC47, BIRC6, WDR18, THOC2, NUP107, REXO4, DDX24, XAB2, UGGT1, ZC3HAV1, YLPM1, NKRF, CCT5, SNW1, DHX30, DIS3, PUF60, COP
Protein Size: 400 - Molecular Weight
- 45 kDa
- Gene ID
- 51547
- NCBI Accession
- NM_016538, NP_057622
- UniProt
- Q9NRC8
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