T-Box 19 antibody (N-Term)

Catalog No. ABIN2779590

Product Details anti-T-Box 19 Antibody

Target: T-Box 19 (TBX19)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This T-Box 19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KPSDGTVSHL LNVVESELQA GREKGDPTEK QLQIILEDAP LWQRFKEVTN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against TBX19. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TBX19

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 448 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for T-Box 19

Target: T-Box 19 (TBX19)

Alternative Name: TBX19 (TBX19 Products)

Synonyms: TBX19 antibody, TBS19 antibody, TPIT antibody, dJ747L4.1 antibody, CH-TBXT antibody, TBXT antibody, AU019250 antibody, D1Ertd754e antibody, Tpit antibody, T-box 19 antibody, TBX19 antibody, Tbx19 antibody

Background: TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.
Alias Symbols: TPIT, TBS19, dJ747L4.1
Protein Interaction Partner: NR5A1,
Protein Size: 448

Molecular Weight: 48 kDa

Gene ID: 9095

NCBI Accession: NM_005149, NP_005140

UniProt: O60806