TLE3 antibody (N-Term)

Catalog No. ABIN2779589

Product Details anti-TLE3 Antibody

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Pig, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TLE3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GSSSGLLALG ALGSQAHLTV KDEKNHHELD HRERESSANN SVSPSESLRA

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against TLE3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TLE3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 772 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TLE3

Target: TLE3 (Transducin-Like Enhancer Protein 3 (TLE3))

Alternative Name: TLE3 (TLE3 Products)

Background: The TLE genes are differentially expressed and encode nuclear proteins, consistent with the presence of sequence motifs associated with nuclear functions. These genes are the human homologues of Drosophila groucho, a member of the Notch signaling pathway which controls a number of different cell-fate choices in invertebrates and vertebrates.
Alias Symbols: ESG, ESG3, GRG3, HsT18976
Protein Interaction Partner: UBC, COPG1, COPZ1, TBC1D4, PIN1, KLC1, COPB1, ARCN1, NLK, UBD, SRXN1, SEC24A, AHCYL1, SSSCA1, ALYREF, UBA2, S100A9, PPM1G, IGBP1, APP, HINFP, tcf7l1a, lnx2b, NDRG1, CUL4B, SIX3, FOXG1, AES, SIX4,
Protein Size: 772

Molecular Weight: 83 kDa

Gene ID: 7090

NCBI Accession: NM_005078, NP_005069

UniProt: Q04726

Pathways: SARS-CoV-2 Protein Interactome