PSMD4/ASF antibody (C-Term)
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- Target See all PSMD4/ASF (Psmd4) Antibodies
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Cow, Sheep, Rabbit, Dog, Guinea Pig, Horse, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PSMD4/ASF antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- VMQDPEFLQS VLENLPGVDP NNEAIRNAMG SLASQATKDG KKDKKEEDKK
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%
- Characteristics
- This is a rabbit polyclonal antibody against PSMD4. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PSMD4
- Top Product
- Discover our top product Psmd4 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 377 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMD4/ASF (Psmd4) (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 4 (Psmd4))
- Alternative Name
- PSMD4 (Psmd4 Products)
- Synonyms
- af-1 antibody, mcb1 antibody, pub-r5 antibody, rpn10 antibody, PSMD4 antibody, DDBDRAFT_0202512 antibody, DDBDRAFT_0232981 antibody, DDB_0202512 antibody, DDB_0232981 antibody, AF antibody, AF-1 antibody, ASF antibody, MCB1 antibody, Rpn10 antibody, S5A antibody, pUB-R5 antibody, xrpn10c antibody, Af1 antibody, Mcb1 antibody, angiocidin antibody, im:6912672 antibody, psmd4 antibody, wu:fc68c04 antibody, zgc:110247 antibody, proteasome 26S subunit, non-ATPase 4 antibody, 26S proteasome non-ATPase regulatory subunit 4 antibody, 26s proteasome non-atpase regulatory subunit 4 (26s proteasomeregulatory subunit s5a) antibody, proteasome 26S subunit, non-ATPase 4 L homeolog antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 antibody, proteasome 26S subunit, non-ATPase 4b antibody, psmd4 antibody, PSMD4 antibody, LOC100194679 antibody, psmD4 antibody, LOC100283637 antibody, Smp_000740.1 antibody, psmd4.L antibody, Psmd4 antibody, psmd4b antibody
- Background
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD4 encodes one of the non-ATPase subunits of the 19S regulator lid.
Alias Symbols: AF, ASF, S5A, AF-1, MCB1, Rpn10, pUB-R5
Protein Interaction Partner: UBC, cdc20, XPC, SPRTN, PSMD14, MDM2, PSMC2, PSMA1, ADRM1, UBQLN1, TXNL1, PSMD3, PSMD2, PSMD1, PSMC6, PSMC4, PSMC1, UCHL5, RPS12, PSMD8, UBQLN4, VCP, GJA1, DIO2, SCHIP1, FBXO6, PARK2, UL76, FBXO25, LOC100044627, Gm4705, LOC677113, Rps6-ps4, Rpl34-ps1, Rpl
Protein Size: 377 - Molecular Weight
- 41 kDa
- Gene ID
- 5710
- NCBI Accession
- NM_002810, NP_002801
- UniProt
- P55036
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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