EYA3 antibody (Middle Region)

Catalog No. ABIN2779571

Product Details anti-EYA3 Antibody

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Cow, Sheep, Horse, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EYA3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QSRKNMTSKN RGKRKADATS SQDSELERVF LWDLDETIII FHSLLTGSYA

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Sheep: 92%

Characteristics: This is a rabbit polyclonal antibody against EYA3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EYA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 573 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EYA3

Target: EYA3 (Eyes Absent Homolog 3 (EYA3))

Alternative Name: EYA3 (EYA3 Products)

Synonyms: zgc:152966 antibody, si:ch211-195b13.2 antibody, Xeya3 antibody, MGC85199 antibody, EYA3 antibody, AI844637 antibody, EYA transcriptional coactivator and phosphatase 3 antibody, EYA transcriptional coactivator and phosphatase 3 L homeolog antibody, eya3 antibody, eya3.L antibody, EYA3 antibody, Eya3 antibody

Background: Eyes absent homolog 3 (EYA3) is a member of the eyes absent (EYA) family of proteins. This protein may act as a transcriptional activator and have a role during development. A similar protein in mice can act as a transcriptional activator. Two transcript variants encoding distinct isoforms have been identified for this gene.
Protein Interaction Partner: UBC, SKI, H2AFX, DACH1, SIX5, SIX4, SIX2, SIX1,
Protein Size: 573

Molecular Weight: 63 kDa

Gene ID: 2140

NCBI Accession: NM_001990, NP_001981

UniProt: Q99504

Pathways: Positive Regulation of Response to DNA Damage Stimulus