MMP19 antibody (N-Term)

Catalog No. ABIN2779559

Product Details anti-MMP19 Antibody

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMP19 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ALRAFQEASE LPVSGQLDDA TRARMRQPRC GLEDPFNQKT LKYLLLGRWR

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against MMP19. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MMP19

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 508 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMP19

Target: MMP19 (Matrix Metallopeptidase 19 (MMP19))

Alternative Name: MMP19 (MMP19 Products)

Synonyms: mmp18 antibody, mmp-18 antibody, mmp-19 antibody, col4 antibody, MMP18 antibody, RASI-1 antibody, matrix metallopeptidase 19 antibody, matrix metallopeptidase 1 S homeolog antibody, mmp19 antibody, mmp1.S antibody, MMP19 antibody, Mmp19 antibody

Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They are also involved in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The function of MMP-19 has not been determined. This gene corresponding to this protein was previously referred to as MMP18 but has been renamed matrix metalloproteinase 19 (MMP19). Multiple transcript variants encoding distict isoforms have been identified for this gene.
Alias Symbols: MMP18, RASI-1
Protein Interaction Partner: ACAN,
Protein Size: 508

Molecular Weight: 56 kDa

Gene ID: 4327

NCBI Accession: NM_002429, NP_002420

UniProt: Q99542