MED16 antibody (C-Term)

Catalog No. ABIN2779553

Product Details anti-MED16 Antibody

Target: MED16 (Mediator Complex Subunit 16 (MED16))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MED16 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RLQFGRAPTL PGSAATLQLD GLARAPGQPK IDHLRRLHLG ACPTEECKAC

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against THRAP5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human THRAP5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 877 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MED16

Target: MED16 (Mediator Complex Subunit 16 (MED16))

Alternative Name: THRAP5 (MED16 Products)

Background: THRAP5 is part of the human thyroid hormone receptor-associated protein (TRAP)-Mediator family which acts as a coactivator for a broad range of nuclear hormone receptors as well as other classes of transcriptional activators.
Alias Symbols: DRIP92, THRAP5, TRAP95
Protein Interaction Partner: HECW2, CDK19, CDK8, UBC, MED19, MED26, EPAS1, FBXW7, MED11, MED8, MED29, MED9, MED18, MED4, RALY, MED13, MED12, MED24, MED21, MED14, MED1, CTDP1, HIST1H3A, MED10, MED25, MED15, VDR, TRA, MED28, OBFC1, ZC3H13, QKI, TADA2A, SUPT7L, SUPT3H, MYC, KAT2A, TRRAP
Protein Size: 877

Molecular Weight: 97 kDa

Gene ID: 10025

NCBI Accession: NM_005481, NP_005472

UniProt: Q9Y2X0

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha