FOXF1 antibody (C-Term)

Catalog No. ABIN2779550

Product Details anti-FOXF1 Antibody

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rabbit, Cow, Guinea Pig, Horse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: PCNPAANPLS GSLSTHSLEQ PYLHQNSHNA PAELQGIPRY HSQSPSMCDR

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against FOXF1. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FOXF1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 354 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-FOXF1 antibody (ABIN2779550)

Tamura, Sasaki, Koyama, Takeda, Idogawa, Tokino: "Forkhead transcription factor FOXF1 is a novel target gene of the p53 family and regulates cancer cell migration and invasiveness." in: Oncogene, Vol. 33, Issue 40, pp. 4837-46, (2014) (PubMed).

Lo, Lee, Chen, Reisman, Berger, Sukumar: "Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas." in: Experimental and molecular pathology, Vol. 94, Issue 1, pp. 262-9, (2013) (PubMed).

Target Details for FOXF1

Target: FOXF1 (Forkhead Box F1 (FOXF1))

Alternative Name: FOXF1 (FOXF1 Products)

Synonyms: ACDMPV antibody, FKHL5 antibody, FREAC1 antibody, FOXF1 antibody, si:dkey-199i24.2 antibody, zgc:158301 antibody, acdmpv antibody, fkhl5 antibody, freac1 antibody, xfd-13 antibody, foxF1 antibody, foxF antibody, AI450827 antibody, Foxf1a antibody, Freac-1 antibody, HFH-8 antibody, Hfh8 antibody, foxf1 antibody, forkhead box F1 antibody, forkhead box F1 L homeolog antibody, forkhead box F1 S homeolog antibody, FOXF1 antibody, foxf1 antibody, foxF1 antibody, Foxf1 antibody, foxf1.L antibody, foxf1.S antibody

Background: This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in the regulation of pulmonary genes as well as embryonic development.
Alias Symbols: FKHL5, ACDMPV, FREAC1
Protein Size: 354

Molecular Weight: 38 kDa

Gene ID: 2294

NCBI Accession: NM_001451, NP_001442

UniProt: Q12946

Pathways: Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process