RLIM antibody (C-Term)

Catalog No. ABIN2779480

Product Details anti-RLIM Antibody

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Pig, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RLIM antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: AQFFLLNEDD DDQPRGLTKE QIDNLAMRSF GENDALKTCS VCITEYTEGN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%, Yeast: 89%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RNF12. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 624 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RLIM

Target: RLIM (Ring Finger Protein, LIM Domain Interacting (RLIM))

Alternative Name: RNF12 (RLIM Products)

Synonyms: NY-REN-43 antibody, RNF12 antibody, AL022832 antibody, AW743871 antibody, Ha1r antibody, Rnf12 antibody, R-LIM antibody, ring finger protein, LIM domain interacting antibody, XRnf12C protein antibody, RLIM antibody, Rlim antibody, xrnf12c antibody, rlim antibody

Background: RNF12 is a RING-H2 zinc finger protein. It has been shown to be a ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Alternatively spliced transcript variants encoding the same protein have been reported.
Alias Symbols: RNF12, NY-REN-43
Protein Interaction Partner: STMN1, SNX17, UBC, RPS14, TNFAIP3, UBE2D1, LNX2, TERF1, SMURF2, HHV8GK18_gp81, HDAC2, REXO1, TOLLIP, LDB1, UBXN1, UBE2E2, SIAH1, SS18L1, STAT6, UBE2D4, UBE2E1, UBE2D3, UBE2D2, LDB2, SIN3A, PDLIM1, LHX1, LHX2, LIMK1, LHX3, ISL1, LMO2, RLIM, ESR1,
Protein Size: 624

Molecular Weight: 69 kDa

Gene ID: 51132

NCBI Accession: NM_016120, NP_057204

UniProt: Q9NVW2