TAF11 antibody (N-Term)

Catalog No. ABIN2779473

Product Details anti-TAF11 Antibody

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TAF11 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MDDAHESPSD KGGETGESDE TAAVPGDPGA TDTDGIPEET DGDADVDLKE

Predicted Reactivity: Cow: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 83%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against TAF11. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TAF11

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 211 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-TAF11 antibody (ABIN2779473)

Anish, Hossain, Jacobson, Takada: "Characterization of transcription from TATA-less promoters: identification of a new core promoter element XCPE2 and analysis of factor requirements." in: PLoS ONE, Vol. 4, Issue 4, pp. e5103, (2009) (PubMed).

Target Details for TAF11

Target: TAF11 (TATA Box Binding Protein Associated Factor 11 (TAF11))

Alternative Name: TAF11 (TAF11 Products)

Synonyms: 1110038O14Rik antibody, 28kDa antibody, AI115401 antibody, AL024207 antibody, AW552398 antibody, PRO214 antibody, TAF2I antibody, TAFII28 antibody, MGC:15243 antibody, TATA-box binding protein associated factor 11 antibody, Taf11 antibody, TAF11 antibody

Background: TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure.
Alias Symbols: TAF2I, PRO2134, TAFII28, MGC:15243
Protein Interaction Partner: APPBP2, MED26, HIST3H3, APP, TBP, ELAVL1, POLR2A, ACTB, TAF8, VDR, THRA, NFYC, NFYB, NFYA, LZTR1, TAF9, TAF12, TAF10, TAF5, TAF13, TAF6, TAF4, TAF7, TAF2, CPSF1, TRIM24, TAF1, RXRB, RXRA, RELA, TAF15, GTF2F1, GTF2E1, GTF2B,
Protein Size: 211

Molecular Weight: 23 kDa

Gene ID: 6882

NCBI Accession: NM_005643, NP_005634

UniProt: Q15544