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DVL2 antibody (N-Term)

DVL2 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779458
  • Target See all DVL2 Antibodies
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Binding Specificity
    • 15
    • 15
    • 11
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 72
    • 32
    • 22
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Zebrafish (Danio rerio), Rabbit, Cow, Dog, Guinea Pig, Horse, Saccharomyces cerevisiae
    Host
    • 69
    • 4
    Rabbit
    Clonality
    • 70
    • 3
    Polyclonal
    Conjugate
    • 29
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DVL2 antibody is un-conjugated
    Application
    • 64
    • 26
    • 20
    • 13
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    AGSSTGGGGV GETKVIYHLD EEETPYLVKI PVPAERITLG DFKSVLQRPA
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 82%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against DVL2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DVL2
    Top Product
    Discover our top product DVL2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 736 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lee, Zhao, Moon, Yoon, Kim, An, Kwon, Hwang, Choi, Shim, Kim, Yang: "Differential involvement of GABA system in mediating behavioral and neurochemical effect of acupuncture in ethanol-withdrawn rats." in: Neuroscience letters, Vol. 443, Issue 3, pp. 213-7, (2008) (PubMed).

  • Target
    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
    Alternative Name
    DVL2 (DVL2 Products)
    Synonyms
    Xdsh antibody, dishevelled antibody, dsh antibody, dvl antibody, Dvl-2 antibody, xdsh antibody, wu:fc05d12 antibody, wu:fo71e09 antibody, wu:fp54a02 antibody, zgc:55372 antibody, dishevelled segment polarity protein 2 antibody, dishevelled segment polarity protein 2 L homeolog antibody, DVL2 antibody, dvl2 antibody, Dvl2 antibody, dvl2.L antibody
    Background
    DVL2 is a member of the dishevelled (dsh) protein family. It is a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: -
    Protein Interaction Partner: UBC, NUMA1, IQGAP1, DVL3, DVL1, RNF185, WWOX, SQSTM1, IRS2, IRS1, TARS, GABARAPL1, CSNK1E, OTULIN, TP53, LYN, Smurf2, PLA2G12A, CTBP2, LRRK2, ATN1, RBFOX1, ITCH, ELAVL1, NHLRC1, MAP1LC3A, GABARAP, VHL, SIRT1, VANGL1, TCEB3B, CPSF7, SNF8, PPM1A, POLI, DYNL
    Protein Size: 736
    Molecular Weight
    79 kDa
    Gene ID
    1856
    NCBI Accession
    NM_004422, NP_004413
    UniProt
    O14641
    Pathways
    Tube Formation
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