ARNTL antibody (N-Term)

Catalog No. ABIN2779410

Product Details anti-ARNTL Antibody

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Cow, Sheep, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARNTL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TDYQESMDTD KDDPHGRLEY TEHQGRIKNA REAHSQIEKR RRDKMNSF

Predicted Reactivity: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against ARNTL. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARNTL

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 625 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ARNTL

Target: ARNTL (Aryl Hydrocarbon Receptor Nuclear Translocator-Like (ARNTL))

Alternative Name: ARNTL (ARNTL Products)

Background: ARNTL is a general dimerization partner for a subset of the basic-helix-loop-helix (bHLH)-PER-ARNT-SIM (PAS) superfamily of transcriptional regulators.
Alias Symbols: TIC, JAP3, MOP3, BMAL1, PASD3, BMAL1c, bHLHe5
Protein Interaction Partner: HIF1A, NPAS2, UBE3A, UBC, DYRK1B, CLOCK, Cry2, SIRT1, BHLHE40, NPAS4, PER3, CRY1, EPAS1, CSNK1E, AHR, HLF, HSP90AA1, SUMO2, SUMO3, RXRA, RARA, KAT2B, EP300,
Protein Size: 625

Molecular Weight: 25 kDa

Gene ID: 406

NCBI Accession: NM_015642, NP_001169

Pathways: Regulation of Lipid Metabolism by PPARalpha, Protein targeting to Nucleus, Warburg Effect