CCBP2 antibody (N-Term)

Catalog No. ABIN2779383

Product Details anti-CCBP2 Antibody

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Binding Specificity: N-Term

Reactivity: Human, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: MAATASPQPL ATEDADSENS SFYYYDYLDE VAFMLCRKDA VVSFGKVFLP

Predicted Reactivity: Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against CCBP2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCBP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 384 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCBP2

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Alternative Name: CCBP2 (CCBP2 Products)

Synonyms: CCBP2 antibody, CCR10 antibody, CCR9 antibody, CMKBR9 antibody, D6 antibody, hD6 antibody, Ccbp2 antibody, LOC733624 antibody, A130091K22Rik antibody, Cmkbr10 antibody, GPR-9-6 antibody, AI464239 antibody, Cmkbr9 antibody, atypical chemokine receptor 2 antibody, atypical chemokine receptor 2-like antibody, chemokine receptor D6 antibody, chemokine (C-C motif) receptor 9 antibody, C-C motif chemokine receptor 9 antibody, ACKR2 antibody, Ackr2 antibody, LOC100219492 antibody, LOC733624 antibody, Ccr9 antibody, CCR9 antibody

Background: CCBP2 is a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown.This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.
Alias Symbols: CCR10, CCR9, CMKBR9, D6, MGC126678, MGC138250, hD6, CCBP2
Protein Interaction Partner: APP, CCL3L3, CCL28, CCL27, CCL21, CCL25, CCL8, CCL19, CCL14, CCL13, CCL11, CCL5, CCL4, CCL3, CCL7, CCL2,
Protein Size: 384

Molecular Weight: 43 kDa

Gene ID: 1238

NCBI Accession: NM_001296, NP_001287

UniProt: O00590