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CLK4 antibody (N-Term)

CLK4 Reactivity: Mouse, Human, Rabbit, Dog, Guinea Pig, Cow, Horse, Rat, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779361
  • Target See all CLK4 Antibodies
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Binding Specificity
    • 9
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 30
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Human, Rabbit, Dog, Guinea Pig, Cow, Horse, Rat, Saccharomyces cerevisiae
    Host
    • 31
    • 1
    Rabbit
    Clonality
    • 32
    Polyclonal
    Conjugate
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLK4 antibody is un-conjugated
    Application
    • 25
    • 19
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RSRRSSPKRK RNRHCSSHQS RSKSHRRKRS RSIEDDEEGH LICQSGDVLR
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 91%
    Characteristics
    This is a rabbit polyclonal antibody against CLK4. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human CLK4
    Top Product
    Discover our top product CLK4 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 481 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Eisenreich, Zakrzewicz, Huber, Thierbach, Pepke, Goldin-Lang, Schultheiss, Pries, Rauch: "Regulation of pro-angiogenic tissue factor expression in hypoxia-induced human lung cancer cells." in: Oncology reports, Vol. 30, Issue 1, pp. 462-70, (2013) (PubMed).

  • Target
    CLK4 (CDC-Like Kinase 4 (CLK4))
    Alternative Name
    CLK4 (CLK4 Products)
    Synonyms
    AI987988 antibody, C85119 antibody, zgc:112975 antibody, CDC like kinase 4 antibody, CDC-like kinase 4 antibody, CDC-like kinase 4b antibody, CLK4 antibody, Clk4 antibody, clk4b antibody
    Background
    The protein encoded by this gene belongs to the CDC2-like protein kinase (CLK) family. This protein kinase can interact with and phosphorylate the serine- and arginine-rich (SR) proteins, which are known to play an important role in the formation of spliceosomes, and thus may be involved in the regulation of alternative splicing. Studies in the Israeli sand rat Psammomys obesus suggested that the ubiquitin-like 5 (UBL5/BEACON), a highly conserved ubiquitin-like protein, may interact with and regulate the activity of this kinase. Multiple alternatively spliced transcript variants have been observed, but the full-length natures of which have not yet been determined.
    Alias Symbols: DKFZp686A20267
    Protein Interaction Partner: KPNA1, KRTAP10-3, KRTAP10-8, KRTAP10-9, KRTAP10-7, CLK4, SRRM2, AHCYL2, SUB1, RASA4, SRPK1, RNF181, CLASRP, UBL5, HSPB2,
    Protein Size: 481
    Molecular Weight
    57 kDa
    Gene ID
    57396
    NCBI Accession
    NM_020666, NP_065717
    UniProt
    Q9HAZ1
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