MXD3 antibody (N-Term)

Catalog No. ABIN2779271

Product Details anti-MXD3 Antibody

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Dog, Rat, Cow, Horse, Rabbit, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MXD3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PIHRRKKRPP QAPGAQDSGR SVHNELEKRR RAQLKRCLER LKQQMPLGAD

Predicted Reactivity: Cow: 93%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 86%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against MXD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MXD3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 206 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-MXD3 antibody (ABIN2779271)

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Target Details for MXD3

Target: MXD3 (MAX Dimerization Protein 3 (MXD3))

Alternative Name: MXD3 (MXD3 Products)

Synonyms: Mad3 antibody, BHLHC13 antibody, MAD3 antibody, MYX antibody, 4631412E13Rik antibody, bHLHc13 antibody, Mad antibody, zgc:66281 antibody, Myx antibody, MAX dimerization protein 3 antibody, Max dimerization protein 3 antibody, MAX dimerization protein 3 L homeolog antibody, mxd3 antibody, MXD3 antibody, Mxd3 antibody, mxd3.L antibody

Background: MXD3 contains 1 basic helix-loop-helix (bHLH) domain. It is a transcriptional repressor and binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Alias Symbols: MYX, MAD3, BHLHC13
Protein Interaction Partner: NOTCH2NL, KRTAP10-7, UBC, NFKB1, MAGEA11, MAX, SIN3A, SMC3,
Protein Size: 206

Molecular Weight: 23 kDa

Gene ID: 83463

NCBI Accession: NM_031300, NP_112590

UniProt: Q9BW11