GLIS2 antibody (N-Term)

Catalog No. ABIN2779249

Product Details anti-GLIS2 Antibody

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Guinea Pig, Horse, Rabbit, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLIS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: QDLVDHVNDY HVKPEKDAGY CCHWEGCARH GRGFNARYKM LIHIRTHTNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GLIS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GLIS2 antibody (ABIN2779249)

Attanasio, Uhlenhaut, Sousa, OToole, Otto, Anlag, Klugmann, Treier, Helou, Sayer, Seelow, Nürnberg, Becker, Chudley, Nürnberg, Hildebrandt, Treier: "Loss of GLIS2 causes nephronophthisis in humans and mice by increased apoptosis and fibrosis." in: Nature genetics, Vol. 39, Issue 8, pp. 1018-24, (2007) (PubMed).

Target Details for GLIS2

Target: GLIS2 (GLIS Family Zinc Finger 2 (GLIS2))

Alternative Name: GLIS2 (GLIS2 Products)

Synonyms: glis2b antibody, nkl-A antibody, xNKLb antibody, NKL antibody, NPHP7 antibody, Gli5 antibody, Klf16 antibody, Nkl antibody, glis2a antibody, nphp7 antibody, GLIS family zinc finger 2 L homeolog antibody, GLIS family zinc finger 2 antibody, GLIS family zinc finger 2 S homeolog antibody, glis2.L antibody, GLIS2 antibody, Glis2 antibody, glis2.S antibody

Background: Members of the Kruppel-like zinc finger protein family, such as GLIS2, function as activators and/or repressors of gene transcription.
Alias Symbols: NKL, NPHP7
Protein Interaction Partner: TRIM32, UBC, PML, BBS2, BBS1, WNK1, XAB2, GPSM2, CPSF1, RBFOX2, SPECC1L, U2AF2, CTNNB1,
Protein Size: 524

Molecular Weight: 56 kDa

Gene ID: 84662

NCBI Accession: NM_032575, NP_115964

UniProt: Q9BZE0