EXOSC4 antibody (N-Term)

Catalog No. ABIN2779148

Product Details anti-EXOSC4 Antibody

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SDQGYRVDGR RAGELRKIQA RMGVFAQADG SAYIEQGNTK ALAVVYGPHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC4. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 245 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC4

Target: EXOSC4 (Exosome Component 4 (EXOSC4))

Alternative Name: EXOSC4 (EXOSC4 Products)

Synonyms: EXOSC4 antibody, zgc:73175 antibody, RRP41 antibody, RRP41A antibody, Rrp41p antibody, SKI6 antibody, Ski6p antibody, hRrp41p antibody, p12A antibody, 1110039I09Rik antibody, 1500001N04Rik antibody, Rrp41 antibody, exosome component 4 antibody, exosome component 4 S homeolog antibody, exosc4 antibody, EXOSC4 antibody, CC1G_03561 antibody, exosc4.S antibody, Exosc4 antibody

Background: EXOSC4 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA. It has a 3'-5' exonuclease activity.
Alias Symbols: SKI6, p12A, RRP41, Ski6p, RRP41A, Rrp41p, hRrp41p
Protein Interaction Partner: EED, TOM1, NMI, H1FX, HIST1H1E, TSEN15, GADD45GIP1, FAHD1, SMPD4, LRRC8D, EXOSC1, EXOSC3, MPZL1, SKIV2L, EXOSC10, EXOSC9, NEK1, HNRNPD, DXO, AICDA, UBC, ESR2, EXOSC5, DDX47, EXOSC2, EXOSC7, EXOSC8, PSIP1, EXOSC6, DIS3L, EXOSC4, SKIV2L2, DIS3, UPF2, MPP6,
Protein Size: 245

Molecular Weight: 27 kDa

Gene ID: 54512

NCBI Accession: NM_019037, NP_061910

UniProt: Q9NPD3