OAS2 antibody (Middle Region)
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- Target See all OAS2 Antibodies
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Pig, Rabbit, Dog, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OAS2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AKGTALKTGS DADLVVFHNS LKSYTSQKNE RHKIVKEIHE QLKAFWREKE
- Predicted Reactivity
- Cow: 92%, Dog: 92%, Human: 100%, Pig: 100%, Rabbit: 85%
- Characteristics
- This is a rabbit polyclonal antibody against OAS2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human OAS2
- Top Product
- Discover our top product OAS2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 719 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))
- Alternative Name
- OAS2 (OAS2 Products)
- Synonyms
- Oasl11 antibody, 2'-5'-oligoadenylate synthetase 2 antibody, 2'-5' oligoadenylate synthetase 2 antibody, 2'-5'-oligoadenylate synthetase 2, 69/71kDa antibody, OAS2 antibody, Oas2 antibody
- Background
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OAS2 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC78578
Protein Interaction Partner: UBC, CLK3, APP,
Protein Size: 719 - Molecular Weight
- 82 kDa
- Gene ID
- 4939
- NCBI Accession
- NM_016817, NP_058197
- UniProt
- P29728
- Pathways
- Hepatitis C
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