CPSF3 antibody (C-Term)

Catalog No. ABIN2779100

Product Details anti-CPSF3 Antibody

Target: CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPSF3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DDSILSVTVD GKTANLNLET RTVECEEGSE DDESLREMVE LAAQRLYEAL

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against CPSF3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CPSF3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 684 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CPSF3

Target: CPSF3 (Cleavage and Polyadenylation Specific Factor 3, 73kDa (CPSF3))

Alternative Name: CPSF3 (CPSF3 Products)

Synonyms: CPSF3 antibody, si:dkey-81b15.1 antibody, wu:fc32f10 antibody, zgc:101655 antibody, CPSF-73 antibody, CPSF73 antibody, cleavage and polyadenylation specific factor 3 antibody, cleavage and polyadenylation specificity factor subunit 3 antibody, cleavage and polyadenylation specific factor 3 L homeolog antibody, cleavage and polyadenylation specific factor 3, 73kDa antibody, cleavage and polyadenylation specificity factor 3 antibody, CPSF3 antibody, cpsf3 antibody, CpipJ_CPIJ011955 antibody, CMU_024380 antibody, PITG_07110 antibody, cpsf3.L antibody, Cpsf3 antibody

Background: CPSF3 belongs to the RNA-metabolizing metallo-beta-lactamase-like family, CPSF3 subfamily. It is component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition.
Alias Symbols: CPSF, YSH1, CPSF73, CPSF-73
Protein Interaction Partner: UBC, SUMO1, WWOX, AICDA, POLR2A, NPM1, TUT1, SYMPK, CSTF2, CPSF2, PAXIP1, MDC1, BARD1, FIP1L1, POLR1E, WDR33, CPSF1, UBD, SIRT7, SMARCAD1, RRAGA, TBP, CDC73, CLP1, PAPOLA, YWHAG,
Protein Size: 684

Molecular Weight: 75 kDa

Gene ID: 51692

NCBI Accession: NM_016207, NP_057291

UniProt: Q9UKF6