NIP7 antibody (C-Term)

Catalog No. ABIN2779096

Product Details anti-NIP7 Antibody

Target: NIP7 (Nuclear Import 7 Homolog (NIP7))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Horse, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NIP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VVVYSMADIP LGFGVAAKST QDCRKVDPMA IVVFHQADIG EYVRHEETLT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%, Yeast: 79%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against NIP7. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NIP7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 180 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NIP7 antibody (ABIN2779096)

Zinzalla, Stracka, Oppliger, Hall: "Activation of mTORC2 by association with the ribosome." in: Cell, Vol. 144, Issue 5, pp. 757-68, (2011) (PubMed).

Target Details for NIP7

Target: NIP7 (Nuclear Import 7 Homolog (NIP7))

Alternative Name: NIP7 (NIP7 Products)

Synonyms: HSPC031 antibody, KD93 antibody, CGI-37 antibody, Nip7p antibody, pEachy antibody, zgc:110384 antibody, nip7 antibody, Nip7 antibody, ACYPI003208 antibody, NIP7 antibody, DKFZp468F182 antibody, 1110017C15Rik antibody, 6330509M23Rik antibody, AA408773 antibody, AA410017 antibody, PEachy antibody, NIP7, nucleolar pre-rRNA processing protein antibody, NIP7, nucleolar pre-rRNA processing protein L homeolog antibody, 60S ribosome subunit biogenesis protein NIP7 homolog antibody, NIP7 antibody, Nip7 antibody, nip7.L antibody, nip7 antibody

Background: NIP7 contains 1PUA domain and belongs to the NIP7 family. It may play a role in 60S ribosomal subunit synthesis.
Alias Symbols: KD93, CGI-37, HSPC031
Protein Interaction Partner: LZTS2, NECAB2, NIP7, CRX, SOX2, UBC, ELAVL1, NOL8, ZBED1,
Protein Size: 180

Molecular Weight: 20 kDa

Gene ID: 51388

NCBI Accession: NM_016101, NP_057185

UniProt: Q9Y221

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly