Pre-mRNA Branch Site Protein p14 (SF3B14) (N-Term) antibody
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- Target See all Pre-mRNA Branch Site Protein p14 (SF3B14) Antibodies
- Pre-mRNA Branch Site Protein p14 (SF3B14)
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Horse, Dog, Rabbit, Guinea Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- Un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SF3B14. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B14
- Top Product
- Discover our top product SF3B14 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 125 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
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- Target
- Pre-mRNA Branch Site Protein p14 (SF3B14)
- Alternative Name
- SF3B14 (SF3B14 Products)
- Synonyms
- 6030419K15Rik antibody, AV001342 antibody, Sf3b14 antibody, zgc:86708 antibody, HSPC175 antibody, Ht006 antibody, P14 antibody, SAP14 antibody, SF3B14a antibody, splicing factor 3B, subunit 6 antibody, splicing factor 3b, subunit 6 antibody, splicing factor 3b subunit 6 S homeolog antibody, splicing factor 3b subunit 6 antibody, Sf3b6 antibody, sf3b6 antibody, sf3b6.S antibody, SF3B6 antibody
- Background
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SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
Protein Interaction Partner: UBC, WWOX, SUZ12, EED, PAN2, ITGA4, FN1, SF3B1, VCAM1, SF3B5, THOC6, WDR18, TRA2A, PRPF19, RBMX, SF3B3, PUF60, DHX15, RCC1, APP, U2AF2, ZNF326, ZC3H18, FTSJ3, PHF5A, TRIM55, SF3B2, UTP14A, USP39, PRPF8, BCAS2, SF3B4, THRAP3, EFTUD2, SRSF11, SART1, VTN, U2
Protein Size: 125 - Molecular Weight
- 14 kDa
- Gene ID
- 51639
- NCBI Accession
- NM_016047, NP_057131
- UniProt
- Q9Y3B4
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