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Pre-mRNA Branch Site Protein p14 (SF3B14) (N-Term) antibody

SF3B14 Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Horse, Dog, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779092
  • Target See all Pre-mRNA Branch Site Protein p14 (SF3B14) Antibodies
    Pre-mRNA Branch Site Protein p14 (SF3B14)
    Binding Specificity
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 28
    • 20
    • 8
    • 7
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Horse, Dog, Rabbit, Guinea Pig
    Host
    • 28
    Rabbit
    Clonality
    • 28
    Polyclonal
    Conjugate
    • 17
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Un-conjugated
    Application
    • 16
    • 9
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    MAMQAAKRAN IRLPPEVNRI LYIRNLPYKI TAEEMYDIFG KYGPIRQIRV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SF3B14. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B14
    Top Product
    Discover our top product SF3B14 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 125 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    Pre-mRNA Branch Site Protein p14 (SF3B14)
    Alternative Name
    SF3B14 (SF3B14 Products)
    Synonyms
    6030419K15Rik antibody, AV001342 antibody, Sf3b14 antibody, zgc:86708 antibody, HSPC175 antibody, Ht006 antibody, P14 antibody, SAP14 antibody, SF3B14a antibody, splicing factor 3B, subunit 6 antibody, splicing factor 3b, subunit 6 antibody, splicing factor 3b subunit 6 S homeolog antibody, splicing factor 3b subunit 6 antibody, Sf3b6 antibody, sf3b6 antibody, sf3b6.S antibody, SF3B6 antibody
    Background
    SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.
    Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a
    Protein Interaction Partner: UBC, WWOX, SUZ12, EED, PAN2, ITGA4, FN1, SF3B1, VCAM1, SF3B5, THOC6, WDR18, TRA2A, PRPF19, RBMX, SF3B3, PUF60, DHX15, RCC1, APP, U2AF2, ZNF326, ZC3H18, FTSJ3, PHF5A, TRIM55, SF3B2, UTP14A, USP39, PRPF8, BCAS2, SF3B4, THRAP3, EFTUD2, SRSF11, SART1, VTN, U2
    Protein Size: 125
    Molecular Weight
    14 kDa
    Gene ID
    51639
    NCBI Accession
    NM_016047, NP_057131
    UniProt
    Q9Y3B4
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