EXOSC7 antibody (N-Term)

Catalog No. ABIN2779075

Product Details anti-EXOSC7 Antibody

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Horse, Rabbit, Guinea Pig, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EVETDVVSNT SGSARVKLGH TDILVGVKAE MGTPKLEKPN EGYLEFFVDC

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC7. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC7

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 291 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC7

Target: EXOSC7 (Exosome Component 7 (EXOSC7))

Alternative Name: EXOSC7 (EXOSC7 Products)

Synonyms: EXOSC7 antibody, zgc:110717 antibody, EAP1 antibody, RRP42 antibody, Rrp42p antibody, hRrp42p antibody, p8 antibody, 2610002K22Rik antibody, AV212732 antibody, mKIAA0116 antibody, exosome component 7 antibody, exosome component 7 S homeolog antibody, exosc7 antibody, EXOSC7 antibody, exosc7.S antibody, Exosc7 antibody

Background: EXOSC7 belongs to the RNase PH family. It is a component of the exosome 3'->5' exoribonuclease complex, a complex that degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions. The protein is required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA.
Alias Symbols: EAP1, FLJ26543, KIAA0116, RRP42, Rrp42p, hRrp42p, p8
Protein Interaction Partner: TP53, UBC, RPA3, RPA2, RPA1, rev, HECW2, EXOSC6, EXOSC2, EXOSC10, DXO, AICDA, EXOSC4, APP, DIS3L, EXOSC3, DIS3, EXOSC1, EXOSC5, SKIV2L2, MPP6, EXOSC8, IP6K1, EXOSC9,
Protein Size: 291

Molecular Weight: 32 kDa

Gene ID: 23016

NCBI Accession: NM_015004, NP_055819

UniProt: B2RDZ9