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RBMXL2 antibody (Middle Region)

RBMXL2 Reactivity: Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2779064
  • Target See all RBMXL2 products
    RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))
    Binding Specificity
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit, Rat
    Host
    • 3
    • 2
    Rabbit
    Clonality
    • 3
    • 2
    Polyclonal
    Conjugate
    • 5
    This RBMXL2 antibody is un-conjugated
    Application
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Sequence
    SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG
    Predicted Reactivity
    Cow: 85%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%
    Characteristics
    This is a rabbit polyclonal antibody against RBMXL2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 392 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))
    Alternative Name
    RBMXL2 (RBMXL2 Products)
    Synonyms
    HNRNPG-T antibody, HNRNPGT antibody, HNRPGT antibody, 1700012H05Rik antibody, Hnrnpg-t antibody, RBMX antibody, hnRNP G-T antibody, RNA binding motif protein, X-linked like 2 antibody, RNA binding motif protein, X-linked-like 2 antibody, RBMXL2 antibody, Rbmxl2 antibody
    Background
    The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
    Alias Symbols: HNRNPG-T, HNRPGT, HNRNPGT
    Protein Interaction Partner: UBC, RABGGTA, FDXACB1, CAND1, COPS5, CUL1, CUL3, CUL4B, SUMO1, DYRK2, TRA2B,
    Protein Size: 392
    Molecular Weight
    43 kDa
    Gene ID
    27288
    NCBI Accession
    NM_014469, NP_055284
    UniProt
    O75526
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