EXOSC2 antibody (N-Term)

Catalog No. ABIN2779057

Product Details anti-EXOSC2 Antibody

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOSC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: RKPLSERLGR DTKKHLVVPG DTITTDTGFM RGHGTYMGEE KLIASVAGSV

Predicted Reactivity: Cow: 79%, Dog: 86%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 91%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EXOSC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOSC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 293 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOSC2

Target: EXOSC2 (Exosome Component 2 (EXOSC2))

Alternative Name: EXOSC2 (EXOSC2 Products)

Synonyms: EXOSC2 antibody, exosc2 antibody, MGC97533 antibody, RRP4 antibody, Rrp4p antibody, hRrp4p antibody, p7 antibody, Rrp4 antibody, fa97b01 antibody, wu:fa97b01 antibody, zgc:110117 antibody, exosome component 2 antibody, exosome component 2 L homeolog antibody, EXOSC2 antibody, exosc2 antibody, Bm1_33895 antibody, PTRG_00114 antibody, Exosc2 antibody, exosc2.L antibody

Background: EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
Alias Symbols: p7, RRP4, Rrp4p, hRrp4p
Protein Interaction Partner: GPX1, ST6GALNAC1, MRPL48, EXOSC7, RNF8, GALNT13, ZNF408, AICDA, METTL22, UBC, UPF1, MDC1, BARD1, EXOSC5, EXOSC4, EXOSC3, DEK, RAN, EXOSC9, DIS3L, DIS3, UBD, CAND1, HDGF, MEPCE, SKIV2L2, EXOSC6, KHSRP, MPP6, EXOSC8, UPF3A, UPF2,
Protein Size: 293

Molecular Weight: 32 kDa

Gene ID: 23404

NCBI Accession: NM_014285, NP_055100

UniProt: Q13868

Pathways: SARS-CoV-2 Protein Interactome