HNRNPH3 antibody (N-Term)

Catalog No. ABIN2779031

Product Details anti-HNRNPH3 Antibody

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPH3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: DYQGRSTGEA FVQFASKEIA ENALGKHKER IGHRYIEIFR SSRSEIKGFY

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against HNRPH3. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HNRPH3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 346 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-HNRNPH3 antibody (ABIN2779031)

Larriba, Casado-Vela, Pendás-Franco, Peña, García de Herreros, Berciano, Lafarga, Casal, Muñoz: "Novel snail1 target proteins in human colon cancer identified by proteomic analysis." in: PLoS ONE, Vol. 5, Issue 4, pp. e10221, (2010) (PubMed).

Papazov, Daskalov: "Effect of contour shape of nervous system electromagnetic stimulation coils on the induced electrical field distribution." in: Biomedical engineering online, Vol. 1, pp. 1, (2004) (PubMed).

Target Details for HNRNPH3

Target: HNRNPH3 (Heterogeneous Nuclear Ribonucleoprotein H3 (2H9) (HNRNPH3))

Alternative Name: HNRPH3 (HNRNPH3 Products)

Synonyms: AA693301 antibody, AI666703 antibody, Hnrph3 antibody, hnrph3 antibody, HNRPH3 antibody, 2H9 antibody, heterogeneous nuclear ribonucleoprotein H3 antibody, heterogeneous nuclear ribonucleoprotein H3 L homeolog antibody, Hnrnph3 antibody, hnrnph3.L antibody, HNRNPH3 antibody

Background: HNRPH3 belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Multiple alternative transcript variants seem to be present for this gene and some appear to have intronic regions in the mRNA. Presently, only two transcript variants are fully described.
Alias Symbols: 2H9, HNRPH3
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, SUMO1, NEDD8, WWOX, ERG, RNF2, EED, rev, PARK2, STK24, HNRNPH3, HNRNPH1, HNRNPF, HNRNPD, HNRNPA1, FN1, DDX5, ITGA4, IL7R, HNRNPU, C17orf85, tat, HCVgp1, HNRNPUL1, HNRNPA0, CHERP, DDX17, VCAM1, RBM4, VCP, PUF60, SF3A3, HNRNPR, HNR
Protein Size: 346

Molecular Weight: 38 kDa

Gene ID: 3189

NCBI Accession: NM_012207, NP_036339

UniProt: P31942