HNRNPA0 antibody (Middle Region)

Catalog No. ABIN2779011

Product Details anti-HNRNPA0 Antibody

Target: HNRNPA0 (Heterogeneous Nuclear Ribonucleoprotein A0 (HNRNPA0))

Binding Specificity: Middle Region

Reactivity: Human, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNRNPA0 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Sequence: KAAVVKFHPI QGHRVEVKKA VPKEDIYSGG GGGGSRSSRG GRGGRGRGGG

Predicted Reactivity: Cow: 93%, Dog: 93%, Human: 100%, Pig: 93%

Characteristics: This is a rabbit polyclonal antibody against HNRPA0. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HNRPA0

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 305 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HNRNPA0

Target: HNRNPA0 (Heterogeneous Nuclear Ribonucleoprotein A0 (HNRNPA0))

Alternative Name: HNRPA0 (HNRNPA0 Products)

Background: HNRPA0 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind RNAs, followed by a glycine-rich C-terminus.
Alias Symbols: HNRPA0
Protein Interaction Partner: UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, EED, RNF2, DYNC1LI1, PSMD13, PSMD12, PSMD8, MAP2, DYNC1I2, DHX9, ABCF1, RPS27, TARDBP, CSF2, NPM1, LMNA, AICDA, MAPKAPK2, GADD45A, U2AF2, VCAM1, SRSF1, NKX3-1, MTNR1A, ITGA4, IL7R, HNRNPK, HNRNPH3, HNRNPH2, HNRN
Protein Size: 305

Molecular Weight: 34 kDa

Gene ID: 10949

NCBI Accession: NM_006805, NP_006796

UniProt: Q13151