SURF6 antibody (Middle Region)

Catalog No. ABIN2779007

Product Details anti-SURF6 Antibody

Target: SURF6 (Surfeit 6 (SURF6))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SURF6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: EPREPPGLIF NKVEVSEDEP ASKAQRRKEK RQRVKGNLTP LTGRNYRQLL

Predicted Reactivity: Cow: 86%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SURF6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SURF6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 361 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SURF6

Target: SURF6 (Surfeit 6 (SURF6))

Alternative Name: SURF6 (SURF6 Products)

Background: This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene, being ubiquitously expressed, and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs, which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties, based on characteristics determined in mouse.This gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. The gene demonstrates features of a housekeeping gene, being ubiquitously expressed, and the encoded protein has been localized to the nucleolus. The protein includes motifs found in both the mouse and fish orthologs, which suggests a putative function as a nucleolar-matrix protein with nucleic acid-binding properties, based on characteristics determined in mouse.
Alias Symbols: RRP14
Protein Interaction Partner: UBC, LIN28A, CSNK2A1, SIRT7,
Protein Size: 361

Molecular Weight: 40 kDa

Gene ID: 6838

NCBI Accession: NM_006753, NP_006744

UniProt: O75683

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly