SLBP antibody (Middle Region)

Catalog No. ABIN2778993

Product Details anti-SLBP Antibody

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Cow, Dog, Zebrafish (Danio rerio), Rat, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLBP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: INYGKNTIAY DRYIKEVPRH LRQPGIHPKT PNKFKKYSRR SWDQQIKLWK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SLBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SLBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 270 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SLBP

Target: SLBP (Stem-Loop Binding Protein (SLBP))

Alternative Name: SLBP (SLBP Products)

Synonyms: CG11886 antibody, Dmel\\CG11886 antibody, SLBP antibody, dSLBP antibody, dSLPB antibody, slbp antibody, cb157 antibody, sb:cb157 antibody, si:dkey-102m7.2 antibody, GB13630 antibody, HBP antibody, slbp1 antibody, xslbp antibody, stem-loop binding protein antibody, Stem-loop binding protein antibody, histone RNA hairpin-binding protein antibody, stem-loop binding protein L homeolog antibody, Slbp antibody, slbp antibody, SLBP antibody, LOC726745 antibody, EHI_178590 antibody, CpipJ_CPIJ008644 antibody, slbp.L antibody

Background: SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
Alias Symbols: HBP
Protein Interaction Partner: UBC, CDK6, CDK4, UPF1, LSM10, ZNF473, USP8, ERI1,
Protein Size: 270

Molecular Weight: 30 kDa

Gene ID: 7884

NCBI Accession: NM_006527, NP_006518

UniProt: Q14493