PAIP1 antibody (N-Term)

Catalog No. ABIN2778987

Product Details anti-PAIP1 Antibody

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Dog, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSDGFDRAPE QTRPLRAPPS SQDKIPQQNS ESAMAKPQVV VAPVLMSKLS

Predicted Reactivity: Cow: 85%, Dog: 86%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PAIP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAIP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 400 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PAIP1 antibody (ABIN2778987)

Fortna, Kim, MacLaren, Marshall, Hahn, Meltesen, Brenton, Hink, Burgers, Hernandez-Boussard, Karimpour-Fard, Glueck, McGavran, Berry, Pollack, Sikela: "Lineage-specific gene duplication and loss in human and great ape evolution." in: PLoS biology, Vol. 2, Issue 7, pp. E207, (2004) (PubMed).

Target Details for PAIP1

Target: PAIP1 (Poly(A) Binding Protein Interacting Protein 1 (PAIP1))

Alternative Name: PAIP1 (PAIP1 Products)

Synonyms: fb53g01 antibody, zgc:91954 antibody, wu:fb53g01 antibody, poly(A) binding protein interacting protein 1 antibody, polyadenylate binding protein-interacting protein 1 antibody, poly(A) binding protein interacting protein 1 S homeolog antibody, PAIP1 antibody, paip1 antibody, Paip1 antibody, paip1.S antibody

Background: PAIP1 interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.The protein encoded by this gene interacts with poly(A)-binding protein and with the cap-binding complex eIF4A. It is involved in translational initiation and protein biosynthesis. Overexpression of this gene in COS7 cells stimulates translation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.
Alias Symbols: MGC12360
Protein Interaction Partner: PABPC1, WWP2, UBC, BMI1, PDCD4, ADSL, CBX6, UPF2, NUBP2, CAND1, UBR5, CUL3, SYNCRIP, CSDE1, HNRNPD, USP12, EIF4A1,
Protein Size: 400

Molecular Weight: 46 kDa

Gene ID: 10605

NCBI Accession: NM_182789, NP_877590