SYNCRIP antibody (Middle Region)
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- Target See all SYNCRIP Antibodies
- SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Rabbit, Zebrafish (Danio rerio), Guinea Pig, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SYNCRIP antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- IEIVFAKPPD QKRKERKAQR QAAKNQMYDD YYYYGPPHMP PPTRGRGRGG
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SYNCRIP. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SYNCRIP
- Top Product
- Discover our top product SYNCRIP Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 623 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).
: "ALS-associated mutations in FUS disrupt the axonal distribution and function of SMN." in: Human molecular genetics, Vol. 22, Issue 18, pp. 3690-704, (2013) (PubMed).
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The spinal muscular atrophy disease protein SMN is linked to the Golgi network." in: PLoS ONE, Vol. 7, Issue 12, pp. e51826, (2013) (PubMed).
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- Target
- SYNCRIP (Synaptotagmin Binding, Cytoplasmic RNA Interacting Protein (SYNCRIP))
- Alternative Name
- SYNCRIP (SYNCRIP Products)
- Synonyms
- GRY-RBP antibody, GRYRBP antibody, HNRNPQ antibody, HNRPQ1 antibody, NSAP1 antibody, PP68 antibody, hnRNP-Q antibody, 2610109K23Rik antibody, 4632417O19Rik antibody, Nsap1 antibody, Nsap1l antibody, pp68 antibody, nsap1 antibody, wu:fe02c03 antibody, wu:fe47h09 antibody, SYNCRIP antibody, hnrpq1 antibody, gry-rbp antibody, rp1-3j17.2 antibody, synaptotagmin binding cytoplasmic RNA interacting protein antibody, synaptotagmin binding, cytoplasmic RNA interacting protein antibody, synaptotagmin binding cytoplasmic RNA interacting protein S homeolog antibody, SYNCRIP antibody, Syncrip antibody, syncrip antibody, syncrip.S antibody
- Background
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Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. SYNCRIP may be involved in translationally coupled mRNA turnover. It implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. It interacts in vitro preferentially with poly(A) and poly(U) RNA sequences.
Alias Symbols: GRY-RBP, NSAP1, RP1-3J17.2, dJ3J17.2, pp68, PP68, GRYRBP, HNRPQ1, hnRNP-Q
Protein Interaction Partner: FUS, PRMT8, UBC, SPRTN, SUMO2, SUMO3, STAU1, MDM2, RPA3, RPA2, RPA1, RNF2, EED, rev, GNB2L1, IQGAP1, RPS21, RPL24, RPL23A, PSMD7, RPSA, IARS, PRMT1, HNRNPU, FKBP3, MAP1S, C14orf166, RPS27L, NELFB, PARK2, FBXO6, TARDBP, CSF2, CD81, IGSF8, HMGA2, ICAM1, HMG
Protein Size: 623 - Molecular Weight
- 69 kDa
- Gene ID
- 10492
- NCBI Accession
- NM_006372, NP_006363
- UniProt
- O60506
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