EMG1 antibody (N-Term)

Catalog No. ABIN2778974

Product Details anti-EMG1 Antibody

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Guinea Pig, Horse, Cow, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EMG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: SLETVKVGKT YELLNCDKHK SILLKNGRDP GEARPDITHQ SLLMLMDSPL

Predicted Reactivity: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 92%, Rat: 93%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against EMG1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EMG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 244 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-EMG1 antibody (ABIN2778974)

Armistead, Khatkar, Meyer, Mark, Patel, Coghlan, Lamont, Liu, Wiechert, Cattini, Koetter, Wrogemann, Greenberg, Entian, Zelinski, Triggs-Raine: "Mutation of a gene essential for ribosome biogenesis, EMG1, causes Bowen-Conradi syndrome." in: American journal of human genetics, Vol. 84, Issue 6, pp. 728-39, (2009) (PubMed).

Target Details for EMG1

Target: EMG1 (EMG1 Nucleolar Protein Homolog (EMG1))

Alternative Name: EMG1 (EMG1 Products)

Synonyms: C2F antibody, Grcc2f antibody, NEP1 antibody, C2f antibody, EMG1, N1-specific pseudouridine methyltransferase antibody, EMG1 N1-specific pseudouridine methyltransferase antibody, EMG1 antibody, Emg1 antibody

Background: EMG1 involved in 40S ribosomal subunit biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing.
Alias Symbols: C2F, NEP1, Grcc2f
Protein Interaction Partner: FAM74A4, UBC, RPA3, RPA2, RPA1, EED, rev, HECW2, IL7R, FN1, BYSL, APP, NEDD8, SLC25A38, NAT6, PSMB7, KHDRBS1, PSME1, HIVEP1, CTSE, ANXA3,
Protein Size: 244

Molecular Weight: 27 kDa

Gene ID: 10436

NCBI Accession: NM_006331, NP_006322

UniProt: Q92979