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SFRS6 antibody (Middle Region)

SRSF6 Reactivity: Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2778972
  • Target See all SFRS6 (SRSF6) Antibodies
    SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))
    Binding Specificity
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 19
    • 12
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig
    Host
    • 15
    • 4
    Rabbit
    Clonality
    • 16
    • 3
    Polyclonal
    Conjugate
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFRS6 antibody is un-conjugated
    Application
    • 9
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    KERTNEGVIE FRSYSDMKRA LDKLDGTEIN GRNIRLIEDK PRTSHRRSYS
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
    Characteristics
    This is a rabbit polyclonal antibody against SFRS6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SFRS6
    Top Product
    Discover our top product SRSF6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 344 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Gautrey, Tyson-Capper: "Regulation of Mcl-1 by SRSF1 and SRSF5 in cancer cells." in: PLoS ONE, Vol. 7, Issue 12, pp. e51497, (2013) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    SFRS6 (SRSF6) (serine/arginine-Rich Splicing Factor 6 (SRSF6))
    Alternative Name
    SFRS6 (SRSF6 Products)
    Synonyms
    B52 antibody, SFRS6 antibody, SRP55 antibody, 1210001E11Rik antibody, AI314910 antibody, AW146126 antibody, Sfrs6 antibody, b52 antibody, sfrs6 antibody, srp55 antibody, sfrs6b antibody, wu:faa54g02 antibody, wu:fc17h09 antibody, zgc:103497 antibody, fa12h12 antibody, sfrs6a antibody, wu:fa12h12 antibody, wu:fa13e06 antibody, zgc:63770 antibody, serine and arginine rich splicing factor 6 antibody, serine/arginine-rich splicing factor 6 antibody, serine/arginine-rich splicing factor 6 S homeolog antibody, serine/arginine-rich splicing factor 6b antibody, serine/arginine-rich splicing factor 6a antibody, SRSF6 antibody, Srsf6 antibody, srsf6.S antibody, srsf6b antibody, srsf6a antibody
    Background
    SFRS6 is involved in mRNA splicing and may play a role in the determination of alternative splicing. It belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12.The protein encoded by this gene is involved in mRNA splicing and may play a role in the determination of alternative splicing. The encoded nuclear protein belongs to the splicing factor SR family and has been shown to bind with and modulate another member of the family, SFRS12. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: B52, MGC5045, SRP55, SFRS6
    Protein Interaction Partner: LUC7L2, TP53, MDM2, ASB18, SUZ12, EED, RPL24, SRPK2, SRPK1, SRPK3, TARDBP, YWHAE, PAN2, TOE1, SF3B4, RBM10, UBC, TRA2B, EIF4A3, MAGOH, ESR1, BARD1, SRSF10, APP, CAND1, COPS5, SRRM1, CUL1, CUL2, TERF2, TERF1, HNRNPA1, SF3A2, ELAVL1, SREK1, AI837181, CLK1,
    Protein Size: 344
    Molecular Weight
    39 kDa
    Gene ID
    6431
    NCBI Accession
    NM_006275, NP_006266
    UniProt
    Q13247
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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