PPIE antibody (Middle Region)

Catalog No. ABIN2778967

Product Details anti-PPIE Antibody

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Guinea Pig, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPIE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RIIPQFMCQG GDFTNHNGTG GKSIYGKKFD DENFILKHTG PGLLSMANSG

Predicted Reactivity: Guinea Pig: 100%, Human: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against PPIE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 235 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPIE

Target: PPIE (Peptidylprolyl Isomerase E (Cyclophilin E) (PPIE))

Alternative Name: PPIE (PPIE Products)

Synonyms: zgc:112471 antibody, CG4886 antibody, CYP33 antibody, Cyp33 antibody, Dcyp33 antibody, Dmel\\CG4886 antibody, PPIE antibody, cyp-33 antibody, cyp33 antibody, cype antibody, CYP-33 antibody, 2010010D16Rik antibody, Ab1-210 antibody, peptidylprolyl isomerase E (cyclophilin E) antibody, cyclophilin-33 antibody, peptidylprolyl isomerase E antibody, peptidylprolyl isomerase E (cyclophilin E) L homeolog antibody, ppie antibody, cyp33 antibody, PPIE antibody, ppie.L antibody, Ppie antibody

Background: PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activityThe protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: CYP33, CYP-33
Protein Interaction Partner: XAB2, BMI1, UBC, EIF4A3, MAGOH, SF3A2, HHV8GK18_gp81, SUMO2, Prpf8, Cdc5l, Snw1, KMT2A, PHYHIP,
Protein Size: 235

Molecular Weight: 26 kDa

Gene ID: 10450

NCBI Accession: NM_203457, NP_982282