BCAS2 antibody (Middle Region)

Catalog No. ABIN2778956

Product Details anti-BCAS2 Antibody

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKLREMESNW VSLVSKNYEI ERTIVQLENE IYQIKQQHGE ANKENIRQDF

Predicted Reactivity: Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against BCAS2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCAS2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 225 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BCAS2 antibody (ABIN2778956)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for BCAS2

Target: BCAS2 (Breast Carcinoma Amplified Sequence 2 (BCAS2))

Alternative Name: BCAS2 (BCAS2 Products)

Background: BCAS2 belongs to the SPF27 family. It is involved in mRNA splicing. The protein might play an important role in breast cancer development by increasing the estrogen receptor's function.
Alias Symbols: DAM1, SPF27, Snt309
Protein Interaction Partner: GOLGA2, KRT40, IKZF3, HGS, AIMP2, TCF4, UBC, RPA3, RPA2, RPA1, SUZ12, EED, RNF2, CSNK2A2, TXNRD2, PPARG, PGR, ESR2, ESR1, POT1, PRPF8, SF3B4, SF1, EP300, CDC5L, PRPF19, EIF4A3, MAGOH, VASN, SF3B6, NCSTN, SNRNP200, ACIN1, HNRNPA0, SRSF10, RBM39, EFTUD2, PR
Protein Size: 225

Molecular Weight: 26 kDa

Gene ID: 10286

NCBI Accession: NM_005872, NP_005863

UniProt: O75934