KARS antibody (C-Term)

Catalog No. ABIN2778941

Product Details anti-KARS Antibody

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KARS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GMGIDRVAMF LTDSNNIKEV LLFPAMKPED KKENVATTDT LESTTVGTSV

Predicted Reactivity: Cow: 92%, Guinea Pig: 85%, Horse: 88%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against KARS. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KARS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 597 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KARS

Target: KARS (Lysyl-tRNA Synthetase (KARS))

Alternative Name: KARS (KARS Products)

Synonyms: CG12141 antibody, Dmel\\CG12141 antibody, KRS antibody, LysRS antibody, cb530 antibody, wu:fa16h02 antibody, zgc:92483 antibody, kars antibody, MGC53345 antibody, kars2 antibody, krs antibody, krs-1 antibody, KARS antibody, Tb06.28P18.190 antibody, CMTRIB antibody, DFNB89 antibody, KARS1 antibody, KARS2 antibody, AA589550 antibody, AL024334 antibody, AL033315 antibody, AL033367 antibody, D8Ertd698e antibody, D8Wsu108e antibody, mKIAA0070 antibody, Lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase antibody, lysyl-tRNA synthetase S homeolog antibody, lysyl-tRNA synthetase L homeolog antibody, LysRS antibody, kars antibody, kars.S antibody, kars.L antibody, Bm1_16500 antibody, lysS antibody, Taci_1118 antibody, Tpau_1737 antibody, Arch_0261 antibody, Trad_2960 antibody, Spirs_3699 antibody, KARS antibody, LOC100280510 antibody, Tb927.6.1510 antibody, Kars antibody

Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.
Alias Symbols: KRS, KARS2, CMTRIB
Protein Interaction Partner: AIMP2, SUMO2, SUMO3, MDM2, UBC, SUMO1, NEDD8, STAT1, SSB, RPL21, RPL19, RPL17, NAP1L4, HSPA4, GPX1, CARS, APEH, CAND1, RANBP6, RPL36, JMJD6, NUDC, IPO7, AIMP1, SH3RF2, FBXO6, vpr, MSK1, gag, FN1, TRMT1, MRPS18B, UBE2S, CCT8, EEF1E1, VBP1, UBA1, RARS, QARS
Protein Size: 597

Molecular Weight: 66 kDa

Gene ID: 3735

NCBI Accession: NM_005548, NP_005539

UniProt: Q15046