AGFG1 antibody (Middle Region)

Catalog No. ABIN2778893

Product Details anti-AGFG1 Antibody

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGFG1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SQSPVVGRSQ GQQQEKKQFD LLSDLGSDIF AAPAPQSTAT ANFANFAHFN

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against HRB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HRB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 562 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AGFG1

Target: AGFG1 (HRB) (HIV-1 Rev Binding Protein (HRB))

Alternative Name: HRB (HRB Products)

Synonyms: HRB antibody, RAB antibody, RIP antibody, AU045498 antibody, C130049H11Rik antibody, C85612 antibody, D730048C23Rik antibody, Hrb antibody, Rip antibody, hrb antibody, agfg1 antibody, wu:fb14f05 antibody, wu:fi19d11 antibody, MGC83726 antibody, MGC97591 antibody, ArfGAP with FG repeats 1 antibody, ArfGAP with FG repeats 1a antibody, ArfGAP with FG repeats 1 S homeolog antibody, KRR1 small subunit processome component homolog antibody, AGFG1 antibody, Agfg1 antibody, agfg1a antibody, agfg1.S antibody, agfg1 antibody, LOC5565923 antibody

Background: HRB is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. HRB binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs.The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. This encoded protein binds the Rev activation domain when Rev is assembled onto its RNA target and can significantly enhance Rev activity when overexpressed. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC116938, MGC116940, RAB, RIP, HRB
Protein Interaction Partner: NYAP2, POLE2, UBC, ALAD, P3H1, NIF3L1, PPME1, IPO11, SH3GLB1, LAP3, TPRKB, DBNL, HSPBP1, GPN1, ARPC1A, ZPR1, OGT, SURF2, LPP, VCAM1, ITGA4, SUCLA2, APP, EPS15, vpr, ITSN1, APC, RNF216, EPS15L1, PKIA, XPO1, AGFG1, VAMP7, CRM1, KAP104,
Protein Size: 562

Molecular Weight: 58 kDa

Gene ID: 3267

NCBI Accession: NM_004504, NP_004495

UniProt: P52594